yirB [2018-07-31 11:32:29]

anti-adaptor protein, inhibits YjbH

Locus: BSU33029

Isoelectric point: 9.93

Molecular weight: 6.60 kDa

Protein length: 54 aa

Gene length: 162 bp

Function: control of proteolysis

Product: anti-adaptor protein

Essential: no

Synonyms: yuzO

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Proteolysis → Additional proteins involved in proteolysis

Gene

Coordinates: 3,387,781 → 3,387,945

The protein

Catalyzed reaction/ biological activity

• prevention of the YjbH-Spx interaction PubMed

Expression and Regulation

Operons

• Genes: yirB
  Description: PubMed

  Regulatory mechanism

  • YuxN: repression, PubMed, in YuxN regulon
  • CssR: activation, CssR-P acts as anti-repressor PubMed, in CssR regulon

  Regulation

  • induced by vancomycin (CssR-P) PubMed
  • induced by cell wall stress (CssR) PubMed

Biological materials

Mutant

• BKE33029 (ΔyirB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTAGATTCACCCTTTC, downstream forward: _UP4_TAAAAAAATAGACTGCAAAA
• BKK33029 (ΔyirB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTAGATTCACCCTTTC, downstream forward: _UP4_TAAAAAAATAGACTGCAAAA

References

Reviews:

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Research papers

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