yirB [2017-03-30 15:17:27]

anti-adaptor protein, inhibits YjbH

locus: BSU33029

pI: 9.93

mw: 6.60 kDa

protein length: 54 aa

gene length: 162 bp

function: control of proteolysis

product: anti-adaptor protein

essential: no

synonyms: yuzO

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]

Gene

Coordinates: 3,387,781 -> 3,387,945

The protein

Catalyzed reaction/ biological activity

• prevention of the [protein|87124945A1CBF7990856FBEB9EAD25096DAC0868|YjbH]-[protein|2C6386E9A63F410558D168798D077DF91590F454|Spx] interaction [Pubmed|21378193]

References

Reviews:

• 23375660

Expression and Regulation

Operons

• genes: [gene|5EC57A51EF2DC48070615653B7A3C1007CFEE01D|yirB]
  description: [pubmed|30001325]

  regulatory mechanism

  • [protein|1D6C340264B8A75727E202AD2E37053091C94013|YuxN]: repression, [pubmed|30001325], in [regulon|1D6C340264B8A75727E202AD2E37053091C94013|YuxN regulon]
  • [protein|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR]: activation, CssR-P acts as anti-repressor [pubmed|30001325], in [regulon|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR regulon]

  regulation

  • induced by vancomycin ([protein|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR]-P) [pubmed|30001325]
  • induced by cell wall stress ([protein|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR]) [pubmed|30001325]