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swrA
master activator of flagellar biosynthesis, modulator of
DegU activity, converts
DegU-P from a repressor to an activator of the fla-che operon, enhances
sigD transcription, controls the number of flagellar basal bodies, inactive pseudogene in strain 168
Product
swarming motility protein
Synonyms
swrAA/1,swrAA,yvzD,ifm
Genomic Context
Categories containing this gene/protein
Gene
Coordinates
3,621,618 3,621,956
Phenotypes of a mutant
loss of swarming motility PubMed The protein
Catalyzed reaction/ biological activity
interacts with the N-terminal domain of DegU to control the activity of DegU PubMed Localization
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operons
Sigma factors
Regulatory mechanism
Additional information
SwrA levels are 3 ... 10-fold increased on solid medium as compared to liquid medium (due to LonA/SmiA-mediated degradation of SwrA in liquid medium) PubMed view in new tabBiological materials
Mutant
MGNA-A376 (yvzD::erm), available at the NBRP B. subtilis, JapanBKE35230 (swrA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCTGTCTTTTAATTGTTCCA, downstream forward: _UP4_TAAACTCTCCTGAGGATATCBKK35230 (swrA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCTGTCTTTTAATTGTTCCA, downstream forward: _UP4_TAAACTCTCCTGAGGATATC References
Reviews
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Original publications
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