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dnaC
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dnaC

replicative DNA helicase, part of the replisome
Locus
BSU_40440
Isoelectric point
4.55
Molecular weight
50.44 kDa
Protein length
454 aa Sequence Blast
Gene length
1365 bp Sequence Blast
Function
DNA replication
Product
replicative DNA helicase
Essential
yes
E.C.
3.6.4.12
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Genetics → DNA replication
  • Groups of genes → Essential genes

    • Gene

    Coordinates
    4,157,471 4,158,835

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • stimulates DnaG primase activity PubMed
  • ATP + H2O --> ADP + H+ + phosphate (according to UniProt)

    • Protein family

  • helicase family (according to UniProt)

    • Domains

  • SF4 helicase domain (aa 179-445) (according to UniProt)

    • Structure

  • 2R6A (Geobacillus stearothermophilus), 2R6C, 2R6D, 2R6E
  • 4M4W (the DnaC-DnaI-DnaG complex) PubMed

    • Localization

  • Cytoplasm (Homogeneous) PubMed

    • Expression and Regulation

    Operons

    Genes
    dnaC
    Description
    PubMed
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    Biological materials

    Two-hybrid system

  • B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Fabian Commichau's lab

    • References

    Reviews

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    Original publications

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