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cwlC [Mon Aug 31 2015 13:54:29 GMT+0200 (CEST)]
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cwlC [Mon Aug 31 2015 13:54:29 GMT+0200 (CEST)]

N-acetylmuramoyl-L-alanine amidase
locus
BSU17410
pI
5.94
mw
27.00 kDa
function
mother cell lysis
product
N-acetylmuramoyl-L-alanine amidase
essential
no
ec
3.5.1.28
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall/ other], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigK regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
  • Protein family

  • N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)
  • [SW|Domains]

  • contains an amidase_3 domain (like [protein|search|CwlD], [protein|search|LytC], [protein|search|YqiI], [protein|search|YrvJ])
  • Structure

  • [PDB|1X60] (peptidoglycan binding domain)
  • [SW|Localization]

  • secreted (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''cwlC'' [Pubmed|8407798]
  • [SW|Sigma factor]

  • [protein|search|SigK] [Pubmed|8407798]
  • Regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|8407798]
  • References

  • 10945275,16042392,11375403,8407798