aroH [Wed Jan 20 2016 13:56:53 GMT+0100 (CET)]

chorismate mutase (isozymes 1 and 2)

locus: BSU22690

pI: 5.00

mw: 14.00 kDa

function: biosynthesis of aromatic amino acids

product: chorismate mutase (isozymes 1 and 2)

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.13|Biosynthesis/ acquisition of aromatic amino acids]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of amino acids]

Gene

Coordinates on the chromosome (coding sequence): 2,377,632 -> 2,378,015

The protein

Catalyzed reaction/ biological activity

• Chorismate = prephenate (according to Swiss-Prot)

Protein family

• BCKDHA family (according to Swiss-Prot)

Structure

• [PDB|2CHT] (complex with a transition state analog)
• [PDB|1DBF]

[SW|Interactions]

• [protein|search|AroH]-[protein|search|AroH]

Expression and Regulation

Operon

• ''[protein|search|aroF]-[protein|search|aroB]-[protein|search|aroH]'' (according to [http://dbtbs.hgc.jp/COG/prom/trpEDCFBA-hisC-tyrA-aroE.html DBTBS])
• ''[protein|search|aroF]-[protein|search|aroB]-[protein|search|aroH]-[protein|search|trpE]-[protein|search|trpD]-[protein|search|trpC]-[protein|search|trpF]-[protein|search|trpB]-[protein|search|trpA]-[protein|search|hisC]-[protein|search|tyrA]-[protein|search|aroE]'' (according to [http://dbtbs.hgc.jp/COG/prom/trpEDCFBA-hisC-tyrA-aroE.html DBTBS])

References

Reviews

• 12698486,9383421

Original publications

• 8378335,25422475,12630863,10960481,2105742,8643526,26278727,26641683,21243152,15034619,14709097