aroH

chorismate mutase (isozymes 1 and 2)

Locus: BSU_22690

Isoelectric point: 5.52

Molecular weight: 14.38 kDa

Protein length: 127 aa

Gene length: 384 bp

Function: biosynthesis of aromatic amino acids

Product: chorismate mutase (isozymes 1 and 2)

Essential: no

E.C.: 5.4.99.5

Synonyms

Genomic Context

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Categories containing this gene/protein

• Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of aromatic amino acids

Gene

Coordinates: 2,377,632 2,378,015

The protein

Catalyzed reaction/ biological activity

• Chorismate --> prephenate (according to UniProt)

Domains

• Chorismate mutase aroH-type domain (aa 3-121) (according to UniProt)

Structure

• 2CHT (complex with a transition state analog) PubMed
• 1DBF

Expression and Regulation

Operons

• Genes: cheR-aroF-aroB-aroH
  Description: PubMed

• Genes: aroF-aroB-aroH
  Description: PubMed

Biological materials

Mutant

• BKE22690 (aroH::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TGCTCCGCGAATTCCGCGAA, downstream forward: _UP4_TAATACGATAAGAACAGCTT
• BKK22690 (aroH::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TGCTCCGCGAATTCCGCGAA, downstream forward: _UP4_TAATACGATAAGAACAGCTT

References

Reviews

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Original publications

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