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catR [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
MarR/DUF24 family transcription repressor of the catD-catE operon
function
resistance against oxidative and electrophile stress
product
MarR/DUF24 family transcription repressor
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress][SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|resistance against oxidative and electrophile stress]Gene
Coordinates on the chromosome (coding sequence)
3,457,615 -> 3,457,941
Phenotypes of a mutant
increased resistance to catechol and quinones [Pubmed|20639328]The protein
Catalyzed reaction/ biological activity
[[MarR/DUF24 family]] transcription repressor of the'' [protein|search|catD]-[protein|search|catE]'' operon [Pubmed|20639328]Protein family
[[MarR/DUF24 family]]Paralogous protein(s)
[protein|search|YodB]Modification
in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of ''[protein|search|catD]-[protein|search|catE]'') [Pubmed|20639328]Labs working on this gene/protein
[SW|Haike Antelmann],University of Greifswald, GermanyReferences