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catR [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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catR [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

MarR/DUF24 family transcription repressor of the catD-catE operon
locus
BSU33680
pI
9.89
mw
26.00 kDa
function
resistance against oxidative and electrophile stress
product
MarR/DUF24 family transcription repressor
essential
no
synonyms
yvaP

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription factors and their control], [SW|resistance against oxidative and electrophile stress]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,457,615 -> 3,457,941

    Phenotypes of a mutant

  • increased resistance to catechol and quinones [Pubmed|20639328]
  • The protein

    Catalyzed reaction/ biological activity

  • [[MarR/DUF24 family]] transcription repressor of the'' [protein|search|catD]-[protein|search|catE]'' operon [Pubmed|20639328]
  • Protein family

  • [[MarR/DUF24 family]]
  • Paralogous protein(s)

  • [protein|search|YodB]
  • Modification

  • in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of ''[protein|search|catD]-[protein|search|catE]'') [Pubmed|20639328]
  • Labs working on this gene/protein

  • [SW|Haike Antelmann],University of Greifswald, Germany
  • References

  • 18282125