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catR [2018-02-11T21:15:20.000Z]
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catR [2018-02-11T21:15:20.000Z]

MarR/DUF24 family transcription repressor of the catD-catE operon
Locus
BSU33680
Isoelectric point
9.89
Molecular weight
26.99 kDa
Protein length
236 aa Sequence Blast
Gene length
708 bp Sequence Blast
Function
resistance against oxidative and electrophile stress
Product
MarR/DUF24 family transcription repressor
Essential
no
Synonyms
yvaP

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,457,615 → 3,457,941

Phenotypes of a mutant

  • increased resistance to catechol and quinones PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • [[MarR/DUF24 family]] transcription repressor of the catD-catE operon PubMed
  • Protein family

  • [[MarR/DUF24 family]]
  • Paralogous protein(s)

    Modification

  • in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of catD-catE) PubMed
  • Expression and Regulation

    Operons

    Biological materials

    Mutant

  • MGNA-A451 (yvaP::erm), available at the NBRP B. subtilis, Japan
  • BKE33680 (ΔcatR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACTTTTCACCTCGTCTG, downstream forward: _UP4_TAATTGCTAAAATGGTTCTG
  • BKK33680 (ΔcatR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACTTTTCACCTCGTCTG, downstream forward: _UP4_TAATTGCTAAAATGGTTCTG
  • Labs working on this gene/protein

  • Haike Antelmann,University of Greifswald, Germany
  • References

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