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ycbD [Mon Aug 31 2015 13:52:10 GMT+0200 (CEST)]
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ycbD [Mon Aug 31 2015 13:52:10 GMT+0200 (CEST)]

NADP(+)-dependent alpha-ketoglutaric semialdehyde dehydrogenase
locus
BSU02470
pI
4.79
mw
52.00 kDa
function
utilization of D-glucarate/galactarate
product
NADP(+)-dependent alpha-ketoglutaric semialdehyde dehydrogenase
essential
no
ec
1.2.1.3
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.14|Utilization of glucarate/galactarate]

    • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]

    • This gene is a member of the following [SW|regulons]

  • [SW|YcbG regulon]

    • The protein

    Catalyzed reaction/ biological activity

  • an aldehyde + NAD+ + H2O = an acid + NADH (according to Swiss-Prot)

    • Protein family

  • aldehyde dehydrogenase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|YfmT], [protein|search|AldY], [protein|search|GabD], [protein|search|GbsA], [protein|search|DhaS], [protein|search|IolA], [protein|search|PutC], [protein|search|RocA], [protein|search|AldX], [protein|search|YwdH]

    • Structure

  • [PDB|3RHH] (from from ''Bacillus halodurans'' C-125 complexed with NADP, 36% identity, 69% similarity)

    • Expression and Regulation

    Regulation

  • induced by D-glucarate/galactarate ([protein|search|YcbG]) [Pubmed|12044674]

    • Regulatory mechanism

  • [protein|search|YcbG]: transcription repression [Pubmed|12044674]

    • References

  • 12044674,17202142