hemZ [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

coproporphyrinogen III oxidase

Locus: BSU09840

Isoelectric point: 5.90

Molecular weight: 57.00 kDa

Function: heme biosynthesis

Product: coproporphyrinogen III oxidase

Essential: no

Synonyms: yhaW, yhaV

Genomic Context

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Categories containing this gene/protein

• Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of heme/ siroheme

Categories containing this gene/protein

• biosynthesis of cofactors, sporulation proteins

This gene is a member of the following regulons

• Rex regulon

Gene

Coordinates on the chromosome (coding sequence): 1,057,680 -> 1,059,185

The protein

Catalyzed reaction/ biological activity

• Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-IX + 2 CO₂ + 2 L-methionine + 2 5'-deoxyadenosine (according to Swiss-Prot)

Protein family

• anaerobic coproporphyrinogen III oxidase family (according to Swiss-Prot)

Paralogous protein(s)

• hemN

Expression and Regulation

Operon

• hemZ PubMed

Sigma factor

• SigA PubMed

Regulation

• induced under anaerobic conditions during growth in the presence of nitrate (no induction in the absence of terminal electron acceptor) (Fnr, ResD, ArfM) PubMed

References

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