You are currently viewing an outdated version of
SubtiWiki.
Please use
the newest version!
hemZ [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
coproporphyrinogen III oxidase
function
heme biosynthesis
product
coproporphyrinogen III oxidase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.6|Biosynthesis of heme/ siroheme][SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|Rex regulon]Gene
Coordinates on the chromosome (coding sequence)
1,057,680 -> 1,059,185
The protein
Catalyzed reaction/ biological activity
Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine (according to Swiss-Prot)Protein family
anaerobic coproporphyrinogen III oxidase family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|hemN]Expression and Regulation
Operon
''[protein|search|hemZ]'' [Pubmed|10498703][SW|Sigma factor]
[protein|search|SigA] [Pubmed|10498703]Regulation
induced under anaerobic conditions during growth in the presence of nitrate (no induction in the absence of terminal electron acceptor) ([protein|search|Fnr], [protein|search|ResD], [protein|search|ArfM]) [Pubmed|10498703]References
