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comP [Thu Mar 03 2016 10:15:25 GMT+0100 (CET)]
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comP [Thu Mar 03 2016 10:15:25 GMT+0100 (CET)]

two-component sensor kinase, detects extracellular ComX
locus
BSU31690
pI
7.00
mw
89.00 kDa
function
regulation of genetic competence and quorum sensing
product
two-component sensor kinase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]
  • [SW|Categories] containing this gene/protein

  • [SW|genetic competence], [SW|protein modification], [SW|transcription factors and their control], [SW|quorum sensing], [SW|membrane proteins], [SW|phosphoproteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,253,529 -> 3,255,838

    Phenotypes of a mutant

  • the mutation suppresses the mucoid phenotype of ''[protein|search|motA]'' or ''[protein|search|motB]'' mutants due to loss of [protein|search|DegU] phosphorylation and concomitant reduced expression of the ''[protein|search|capB]-[protein|search|capC]-[protein|search|capA]-[protein|search|capE]'' operon [Pubmed|24296669]
  • The protein

    Catalyzed reaction/ biological activity

  • autophosphorylation, phosphorylation of [protein|search|ComA]
  • [SW|Domains]

  • eight transmembrane segments
  • Modification

  • autophosphorylation on a His residue
  • Effectors of protein activity

  • [protein|search|ComX] (extracellular)
  • [SW|Localization]

  • cell membrane [Pubmed|18763711]
  • [SW|Interactions]

  • [protein|search|ComP]-[protein|search|ComA]
  • Expression and Regulation

    Operon

  • ''comP'' [Pubmed|9274030]
  • References

    Reviews

  • 12576575
  • Original Publications

  • 11133937,8643670,12067344,10094672,10419951,2116363,9274030,18763711,24296669,24130811,24425772,24788106,25757097,26787913