SubtiBank SubtiBank
sufB
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

sufB

FeS scaffold, synthesis of Fe-S-clusters
Locus
BSU_32670
Isoelectric point
4.96
Molecular weight
52.56 kDa
Protein length
465 aa Sequence Blast
Gene length
1398 bp Sequence Blast
Function
synthesis of iron-sulfur clusters
Product
FeS scaffold
Essential
yes
Synonyms
yurU
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Iron metabolism → Biosynthesis of iron-sulfur clusters
  • Groups of genes → Essential genes

    • Gene

    Coordinates
    3,355,593 3,356,990

    Phenotypes of a mutant

  • essential PubMed
  • the mutant is viable and Fe-S clusters are dispensable if IspG and IspH from the MEP pathway for isoprenoid biosynthesis are bypassed by a heterologous mevalonate pathway which allows B. subtilis to synthesize isopentenyl diphosphate and diphosphomevalonate PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • synthesis of Fe-S-clusters (the SufB-SufC-SufD complex) PubMed

    • Protein family

  • UPF0051 (ycf24) family (with SufD, according to UniProt)

    • Cofactors

  • Fe-S cluster PubMed

    • Structure

  • 5AWF (from E. coli, the SufB-SufC-SufD complex, 41% identity) PubMed

    • Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed
  • belongs to the 100 most abundant proteins PubMed

    • Expression and Regulation

    Operons

    Genes
    sufC-sufD-sufS-sufU-sufB
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B583 (yurU::erm), available at the NBRP B. subtilis, Japan

    • References

    Reviews

    Loading

    Original publications

    Loading