opuD

glycine betaine and arsenobetaine transporter

Locus: BSU_30070

Isoelectric point: 9.51

Molecular weight: 55.95 kDa

Protein length: 512 aa

Gene length: 1539 bp

Function: compatible solute transport

Product: glycine betaine transporter

Essential: no

Synonyms: ytfQ

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Uptake of compatible solutes
• Lifestyles → Coping with stress → Coping with hyper-osmotic stress
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,076,818 3,078,356

The protein

Catalyzed reaction/ biological activity

• uptake of glycine betaine and arsenobetaine PubMed

Protein family

• BCCT transporter (TC 2.A.15) family (single member, according to UniProt)

Structure

• 4AIN (BetP from Corynebacterium glutamicum, 44% identity) PubMed

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: ytfP-opuD
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigB: sigma factor, PubMed, in SigB regulon

  Regulation

  • induced by cold stress PubMed

Biological materials

Mutant

• MGNA-A815 (opuD::erm), available at the NBRP B. subtilis, Japan
• 1A1052 ( opuD::kan), PubMed, available at BGSC
• 1A1053 ( opuD::kan), PubMed, available at BGSC
• 1A1054 ( opuD::kan), PubMed, available at BGSC
• 1A1055 ( opuD::kan), PubMed, available at BGSC
• BKE30070 (opuD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTCTCACCCTCTAATTT, downstream forward: _UP4_TAACAAAAAAGATCTTTCCG
• BKK30070 (opuD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTCTCACCCTCTAATTT, downstream forward: _UP4_TAACAAAAAAGATCTTTCCG

Labs working on this gene/protein

• Erhard Bremer, University of Marburg, Germany homepage

References

Reviews

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Original publications

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