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ytpB [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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ytpB [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

tetraprenyl-beta-curcumene synthase, catalyzes the first committed step in C35 terpenoid biosynthesis, salt stress protein
locus
BSU30500
pI
5.76
mw
42.00 kDa
function
C35 terpenoid biosynthesis
product
tetraprenyl-beta-curcumene synthase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]

    • [SW|Categories] containing this gene/protein

  • [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigM regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,121,538 -> 3,122,641

    Phenotypes of a mutant

  • increased sensitivity to bacitracin, due to the accumulation of heptaprenyl pyrophosphate [Pubmed|24806199]
  • sensitivity is increased in a ''[protein|search|ytpB] [protein|search|menA]'' double mutant [Pubmed|24806199]

    • Expression and Regulation

    Operon

  • ''[protein|search|ytpA]-[protein|search|ytpB]'' [Pubmed|18179421]
  • ''[protein|search|ytpB]'' [Pubmed|9387221]

    • [SW|Sigma factor]

  • ''[protein|search|ytpA]'': [protein|search|SigM] [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]

    • Regulation

  • expressed under conditions of salt stress ([protein|search|SigM]) [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]

    • References

  • 9387221,18179421,23748782,21627333,24806199