cysP [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

sulfate transport in via proton symport

locus: BSU15580

pI: 10.27

mw: 36.00 kDa

function: sulfate uptake

product: sulfate transport in via proton symport

essential: no

synonyms: ylnA

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.2|sulfur metabolism/ general]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|sulfur metabolism], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|CymR regulon], [SW|S-box]

Gene

Coordinates on the chromosome (coding sequence): 1,631,095 -> 1,632,159

The protein

[SW|Localization]

• cell membrane

Expression and Regulation

Operon

• ''[protein|search|cysH]-[protein|search|cysP]-[protein|search|sat]-[protein|search|cysC]-[protein|search|ylnD]-[protein|search|ylnE]-[protein|search|ylnF]'' [Pubmed|11004190]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|11004190]

Regulation

• repressed by casamino acids [Pubmed|12107147]
• repressed in the presence of cysteine ([protein|search|CymR])
• induced by methionine starvation ([protein|search|S-box]) [Pubmed|10094622]

Regulatory mechanism

• [protein|search|S-box]: transcription termination/ antitermination, the [protein|search|S-box] [SW|riboswitch] binds S-adenosylmethionine resulting in termination [Pubmed|10094622]
• [protein|search|CymR]: transcription repression

Labs working on this gene/protein

• [[Isabelle Martin-Verstraete]], Institute Pasteur, Paris, France

References

• 16267287,18039762,12107147