ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)
function
acquisition of iron
product
ABC transporter for the siderophores Fe-enterobactin
and Fe-bacillibactin (integral membrane protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.5|Uptake of iron/ siderophores][category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.1|ABC transporters for the uptake of iron/ siderophores][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.4|ABC transporters for the uptake of iron/ siderophores][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|Btr regulon], [SW|CitB regulon], [SW|Fur regulon]The protein
Protein family
FecCD subfamily (according to Swiss-Prot)[SW|Localization]
cell membrane [Pubmed|10092453][SW|Interactions]
[protein|search|YusV]-([protein|search|FeuB]-[protein|search|FeuC])-[protein|search|FeuA] [Pubmed|10092453]Expression and Regulation
Operon
''[protein|search|feuA]-[protein|search|feuB]-[protein|search|feuC]-[protein|search|ybbA]'' [Pubmed|12354229][SW|Sigma factor]
[protein|search|SigA] [Pubmed|17725565]Regulation
repressed in the presence of iron ([protein|search|Fur], [protein|search|CitB]) [Pubmed|12354229]induced in the presence of iron chelators bacillibactin or enterobactin ([protein|search|Btr]) [Pubmed|17725565]Regulatory mechanism
[protein|search|Fur]: transcription repression [Pubmed|12354229][protein|search|CitB]: binding to the iron responsive element in the absence of iron[protein|search|Btr]: transcription activation in the presence of the co-activators bacillibactin or enterobactin [Pubmed|17725565]References
19746494,16672620,10092453,16889643,17725565,12354229 
