nprB [Wed Jun 15 2016 16:33:31 GMT+0200 (CEST)]

extracellular neutral protease B

locus: BSU11100

pI: 5.00

mw: 59.00 kDa

function: degradation of proteins

product: extracellular neutral protease B

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.5|Utilization of proteins]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.2|Extracellular feeding proteases]
• [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]

[SW|Categories] containing this gene/protein

• [SW|utilization of nitrogen sources other than amino acids], [SW|proteolysis]

Gene

Coordinates on the chromosome (coding sequence): 1,186,037 -> 1,187,653

The protein

Catalyzed reaction/ biological activity

• Similar, but not identical, to that of thermolysin (according to Swiss-Prot)

Protein family

• peptidase M4 family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|NprE]

[SW|Localization]

• secreted (according to Swiss-Prot)

Biological materials

Mutant

• BKE11100 (''ΔaprE::erm trpC2''), available at BGSC
• KO7 (''ΔnprE ΔaprE Δepr Δmpr ΔnprB Δvpr Δbpr''), available as BGSC 1A1133

References

Reviews

• 20735481

Original publications

• 24115457