sunI [Mon Aug 31 2015 13:55:07 GMT+0200 (CEST)]

bacteriocin producer immunity protein

locus: BSU21490

pI: 9.00

mw: 12.00 kDa

function: immunity to sublancin

product: bacteriocin producer immunity protein

essential: yes

synonyms: yolF

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|resistance against toxins/ antibiotics], [SW|toxins, antitoxins and immunity against toxins], [SW|SP-beta prophage], [SW|membrane proteins], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence): 2,269,988 -> 2,270,305

Phenotypes of a mutant

• essential (facultative, ''[protein|search|sunI]'' can be deleted if ''[protein|search|sunA]'' is also absent) [Pubmed|19047653]

The protein

Catalyzed reaction/ biological activity

• mediates immunity to sublancin [Pubmed|19047653]

Protein family

• ribosomal protein S1P family (according to Swiss-Prot)

[SW|Localization]

• membrane anchored protein [Pubmed|19047653] [Pubmed|18763711]

Expression and Regulation

Operon

• ''[protein|search|sunI]'' [Pubmed|22383849]

Biological materials

Mutant

• GP1565 (''[protein|search|sunA]-[protein|search|sunI]'', aphA3), available in [SW| Jörg Stülke]'s lab

Labs working on this gene/protein

• [SW|Jan Maarten van Dijl], Groningen, Netherlands

References

• 18763711,19047653,22383849