yxjH [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

putative methionine synthase

locus: BSU38950

pI: 5.00

mw: 38.00 kDa

function: unknown

product: putative methionine synthase

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.11|Biosynthesis/ acquisition of methionine/ S-adenosylmethionine/ based on similarity]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of amino acids]

This gene is a member of the following [SW|regulons]

• [SW|S-box]

Gene

Coordinates on the chromosome (coding sequence): 3,997,964 -> 3,999,097

The protein

Paralogous protein(s)

• [protein|search|YxjG]

Structure

• [PDB|1YPX] (the enzyme from ''Listeria monocytogenes'', 50% identity)

Expression and Regulation

Operon

• ''[protein|search|yxjH]'' [Pubmed|10746760]

Regulation

• repressed by casamino acids [Pubmed|12107147]
• induced by methionine starvation ([protein|search|S-box]) [Pubmed|10094622]

Regulatory mechanism

• [protein|search|S-box]: transcription termination/ antitermination, the [protein|search|S-box] [SW|riboswitch] binds S-adenosylmethionine resulting in termination [Pubmed|10094622]

References

• 19258532,10094622,18039762,12107147