gltR [Mon Jun 06 2016 12:41:42 GMT+0200 (CEST)]

transcriptional regulator (LysR family)

locus: BSU26670

pI: 6.00

mw: 32.00 kDa

function: unknown

product: transcriptional regulator (LysR family)

essential: no

synonyms: yrdL

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

[SW|Categories] containing this gene/protein

• [SW|transcription factors and their control]

This gene is a member of the following [SW|regulons]

• [SW|GltR regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,725,837 -> 2,726,727

Phenotypes of a mutant

• The function of this protein is unknown. However, certain mutant forms are able to activate expression of the ''[protein|search|gltA]-[protein|search|gltB]'' operon (and thus to replace the cognate activator protein [protein|search|GltC])

The protein

Protein family

• [SW|LysR family] of transcription factors

Additional information

• The function of this protein is unknown. However, certain mutant forms are able to activate expression of the ''[protein|search|gltA]-[protein|search|gltB]'' operon (and thus to replace the cognate activator protein [protein|search|GltC])

Expression and Regulation

Operon

• ''gltR'' (according to [http://dbtbs.hgc.jp/COG/prom/gltR.html DBTBS])

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|9023181]

Regulatory mechanism

• [protein|search|GltR]: negative autoregulation [Pubmed|9023181]

Biological materials

Mutant

• GP345 (erm), available in the [SW|Stülke] lab

Labs working on this gene/protein

• [SW|Linc Sonenshein], Tufts University, Boston, MA, USA [http://www.tufts.edu/sackler/microbiology/faculty/sonenshein/index.html Homepage]

References

• 9023181