gltR [2017-02-27 15:02:04]

transcriptional regulator (LysR family)

locus: BSU26670

pI: 6.00

mw: 32.00 kDa

protein length: 296 aa

gene length: 888 bp

function: unknown

product: transcriptional regulator (LysR family)

essential: no

synonyms: yrdL

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

This gene is a member of the following [SW|regulons]

• [SW|GltR regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,725,837 -> 2,726,727

Phenotypes of a mutant

• The function of this protein is unknown. However, certain mutant forms are able to activate expression of the ''[gene|44DF1B7E476AD58B3CCC39300FFE0132D0D32AD0|gltA]-[gene|AA07CC52B2DD48ACC9D3375E9D531CB1ACBE485A|gltB]'' operon (and thus to replace the cognate activator protein [protein|87BCAE725B02860156D50E1783F6DB68510C811E|GltC])

The protein

Protein family

• [SW|LysR family] of transcription factors

Additional information

• The function of this protein is unknown. However, certain mutant forms are able to activate expression of the ''[gene|44DF1B7E476AD58B3CCC39300FFE0132D0D32AD0|gltA]-[gene|AA07CC52B2DD48ACC9D3375E9D531CB1ACBE485A|gltB]'' operon (and thus to replace the cognate activator protein [protein|87BCAE725B02860156D50E1783F6DB68510C811E|GltC])

Expression and Regulation: [[this]]

Biological materials

Mutant

• GP345 (erm), available in the [SW|Stülke] lab

Expression vector

• pBP421 (N-terminal Strep-tag, for [SW|SPINE], purification from ''B. subtilis'', in [SW|pGP382]) (available in [SW|Fabian Commichau]'s lab)

Labs working on this gene/protein

• [SW|Linc Sonenshein], Tufts University, Boston, MA, USA [http://www.tufts.edu/sackler/microbiology/faculty/sonenshein/index.html Homepage]

References

• 9023181