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proH [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]
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proH [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

pyrroline-5-carboxylate reductase
Locus
BSU18480
Isoelectric point
7.00
Molecular weight
31.00 kDa
Function
osmoadaptive de novo production of proline
Product
pyrroline-5-carboxylate reductase
Essential
no
E.C.
1.5.1.2
Synonyms
yoxE

Genomic Context

      
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Categories containing this gene/protein

Categories containing this gene/protein

Gene

Coordinates on the chromosome (coding sequence)
2,016,845 -> 2,017,738

The protein

Catalyzed reaction/ biological activity

  • L-proline NAD(P) = 1-pyrroline-5-carboxylate NAD(P)H (according to Swiss-Prot)
  • Protein family

  • glutamate 5-kinase family (according to Swiss-Prot)
  • Paralogous protein(s)

    Structure

  • 5BSE (from Medicago trunculata, 36% identity)
  • Localization

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operon

    Sigma factor

    Regulation

  • expressed under conditions of osmotic stress PubMed
  • induced by cold stress PubMed
  • expression during spore germination is increased under conditions of osmotic stress PubMed
  • References

    Reviews

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    Original publications

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