lytT [2019-08-28 12:30:32]

two-component response regulator, control of pyruvate utilization

locus: BSU_28920

pI: 5.08

mw: 27.68 kDa

protein length: 241 aa

gene length: 726 bp

function: control of pyruvate utilization

product: two-component response regulator

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.1|Autolysis]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue]

Gene

Coordinates: 2,955,783 2,956,508

The protein

Modification

• phosphorylated on Asp by [protein|02FAD7D3A73CC0462D0116F4E5BA9505CBF7FCDD|LytS]

[SW|Localization]

• cytoplasm (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|02FAD7D3A73CC0462D0116F4E5BA9505CBF7FCDD|lytS]-[gene|53BA24E91EEC797C95B8975C487F3C50CBBFA2E3|lytT]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A014 (lytT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/14 NBRP B. subtilis, Japan]
• BKE28920 ([gene|53BA24E91EEC797C95B8975C487F3C50CBBFA2E3|lytT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCATCCCTTGCCAGCATCT, downstream forward: _UP4_TGATGGGCGGCTTTTTGCAT
• BKK28920 ([gene|53BA24E91EEC797C95B8975C487F3C50CBBFA2E3|lytT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCATCCCTTGCCAGCATCT, downstream forward: _UP4_TGATGGGCGGCTTTTTGCAT

References

Reviews

• 29208748,29354650

Original publications

• 10094672,8969504,27422364,28974613