aroK [Wed Feb 15 2017 18:42:35 GMT+0100 (CET)]

shikimate kinase

locus: BSU03150

pI: 5.00

mw: 21.00 kDa

function: biosynthesis of aromatic amino acids

product: shikimate kinase

essential: yes

ec: 2.7.1.71

synonyms: aroI

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.13|Biosynthesis/ acquisition of aromatic amino acids]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of amino acids]

Gene

Coordinates on the chromosome (coding sequence): 340,025 -> 340,585

Phenotypes of a mutant

• essential [Pubmed|28189581]

The protein

Catalyzed reaction/ biological activity

• ATP shikimate = ADP shikimate 3-phosphate (according to Swiss-Prot)

Protein family

• shikimate kinase family (according to Swiss-Prot)

Structure

• [PDB|2PT5] (from ''A. aeolicus'', 39% identity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operon

• ''aroK'' (according to [http://dbtbs.hgc.jp/COG/prom/aroK.html DBTBS])

References

• 170268,4200844,4974400,24158146,28189581