pucR [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

transcriptional regulator of puc genes

locus: BSU32420

pI: 6.19

mw: 60.00 kDa

function: regulation of purine utilization

product: transcriptional regulator of puc genes (PucR family)

essential: no

synonyms: yunI

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

[SW|Categories] containing this gene/protein

• [SW|utilization of nucleotides], [SW|transcription factors and their control]

This gene is a member of the following [SW|regulons]

• [SW|PucR regulon], [SW|TnrA regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,328,762 -> 3,330,357

The protein

Protein family

• [SW|PucR family]

Expression and Regulation

Operon

• ''[protein|search|pucR]-[protein|search|pucJ]-[protein|search|pucK]-[protein|search|pucL]-[protein|search|pucM]'' [Pubmed|12823818]

Regulation

• repressed by purine nucleotides (effector: allantoin) ([protein|search|PucR]) [Pubmed|12029039]

Regulatory mechanism

• [protein|search|PucR]: transcription auto-repression [Pubmed|12029039]
• [protein|search|TnrA]: transcription activation [Pubmed|25755103]

References

• 12374841,11344136,12029039,12823818,25755103