GTPase, activity stimulated by ribosomes, may be involved in ribosome maturation
function
ribosome assembly, coordination of peptidoglycan deposition in the cell wall
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other][category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.9|Newly identified competence genes][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.6|Ribosome assembly][category|SW 6|Groups of genes] → [category|SW 6.3|GTP-binding proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.6|Phosphorylation on a Thr residue][SW|Categories] containing this gene/protein
[SW|cell wall/ other], [SW|translation], [SW|GTP-binding proteins], [SW|phosphoproteins]Gene
Coordinates on the chromosome (coding sequence)
1,653,103 -> 1,653,999
Phenotypes of a mutant
forms curly cells [Pubmed|22544754]The protein
Protein family
engC GTPase domain (according to Swiss-Prot)Modification
''in vitro'' phosphorylated on Thr-166 by [protein|search|PrkC], dephosphorylated by [protein|search|PrpC] [Pubmed|22544754,19246764]Structure
[PDB|1T9H][SW|Interactions]
binds the 30S subunit of the ribosome [Pubmed|22544754]Expression and Regulation
Operon
''[protein|search|prpC]-[protein|search|prkC]-[protein|search|cpgA]'' [Pubmed|16025310]''[protein|search|cpgA]'' [Pubmed|16025310]Labs working on this gene/protein
[SW|Tony Wilkinson], York University, U.K. [http://www.york.ac.uk/depts/chem/staff/ajw.html homepage]References
Reviews
Original publications
15223319,16485133,14747714,22544754,18344364,19246764,19246764,15828870,17005971,18344364,18984160