yhdY [2017-10-15 16:35:38]

mechanosensitive channel, similar to [protein|search|MscS]

locus: BSU09640

pI: 5.76

mw: 42.38 kDa

protein length: 371 aa

gene length: 1113 bp

function: resistance to osmotic downshock

product: mechanosensitive channel, similar to [protein|search|MscS]

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.7|Coping with hypo-osmotic stress]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 1,038,909 → 1,040,024

The protein

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]
  description: [Pubmed|21815947]

Biological materials

Mutant

• MGNA-A701 (yhdY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/701 NBRP B. subtilis, Japan]
• 1A958 ( ''yhdY''::''erm''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A958&Search=1A958 BGSC]
• 1A958 ( ''yhdY''::''erm''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A958&Search=1A958 BGSC]
• BKE09640 (Δ[gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTGTCTCCCCTCTAT, downstream forward: _UP4_TAAAAGAGAGACTTCGTCTG
• BKK09640 (Δ[gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTGTCTCCCCTCTAT, downstream forward: _UP4_TAAAAGAGAGACTTCGTCTG

Labs working on this gene/protein

• [SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]

References

Reviews

• 12626684,22685280

Original Publications

• 17665170,18310427,19252899,21815947,26883633