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yhdY [2018-09-06 18:53:21]
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yhdY [2018-09-06 18:53:21]

mechanosensitive channel, similar to [protein|search|MscS]
locus
BSU09640
pI
5.76
mw
42.38 kDa
protein length
371 aa Sequence Blast
gene length
1113 bp Sequence Blast
function
resistance to osmotic downshock
product
mechanosensitive channel, similar to [protein|search|MscS]
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.7|Coping with hypo-osmotic stress]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,038,909 → 1,040,024

    The protein

    Structure

  • [PDB|4AGE] (corresponds to aa 129 ... 358 of YhdY, 27% identity)

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]
    description
    [Pubmed|21815947]
    view in new tab

    additional information

  • the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]

    • Biological materials

    Mutant

  • MGNA-A701 (yhdY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/701 NBRP B. subtilis, Japan]
  • 1A958 ( ''yhdY''::''erm''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A958&Search=1A958 BGSC]
  • 1A958 ( ''yhdY''::''erm''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A958&Search=1A958 BGSC]
  • BKE09640 (Δ[gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTGTCTCCCCTCTAT, downstream forward: _UP4_TAAAAGAGAGACTTCGTCTG
  • BKK09640 (Δ[gene|50DC162B3A7798F8D10B8373968AD333F197360B|yhdY]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACTGTCTCCCCTCTAT, downstream forward: _UP4_TAAAAGAGAGACTTCGTCTG

    • Labs working on this gene/protein

  • [SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]

    • References

    Reviews

  • 12626684,22685280

    • Original Publications

  • 17665170,18310427,19252899,21815947,26883633