nupC [Mon Aug 31 2015 13:57:38 GMT+0200 (CEST)]

pyrimidine nucleoside transport protein

locus: BSU39410

pI: 9.32

mw: 42.00 kDa

function: pyrimidine uptake

product: pyrimidine nucleoside transport protein

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.6|Nucleotide/ nucleoside transporter]
• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|utilization of nucleotides], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon], [SW|DeoR regulon]

The protein

Protein family

• SLC28A transporter family (according to Swiss-Prot)

[SW|Localization]

• membrane protein [Pubmed|18763711]

Expression and Regulation

Operon

• ''[protein|search|dra]-[protein|search|nupC]-[protein|search|pdp]'' [Pubmed|8550462]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|8550462]

Regulation

• repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
• induced by deoxynucleotides ([protein|search|DeoR]) [Pubmed|8550462]

Regulatory mechanism

• [protein|search|CcpA]: transcription repression [Pubmed|10666464]
• [protein|search|DeoR]: transcription repression [Pubmed|8550462]

References

• 11065368,8550462,10074062,18763711,10666464