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nupC
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nupC

pyrimidine nucleoside transport protein
Locus
BSU_39410
Isoelectric point
9.32
Molecular weight
42.37 kDa
Protein length
393 aa Sequence Blast
Gene length
1182 bp Sequence Blast
Function
pyrimidine uptake
Product
pyrimidine nucleoside transport protein
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → Transporters/ other → Nucleotide/ nucleoside transporter
  • Metabolism → Nucleotide metabolism → Utilization of nucleotides
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    4,050,340 4,051,521

    The protein

    Protein family

  • concentrative nucleoside transporter (CNT) (TC 2.A.41) family (with YutK and NupG, according to UniProt)

    • Structure

  • 3TIJ (from Vibrio cholerae, 33% identity) PubMed

    • Localization

  • membrane protein PubMed

    • Expression and Regulation

    Operons

    Genes
    dra-nupC-pdp
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon
  • DeoR: repression, PubMed, in DeoR regulon

    • Regulation

  • induced by deoxynucleotides (DeoR) PubMed
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    Biological materials

    Mutant

  • BKE39410 (nupC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTGTTTCTCCTTTAT, downstream forward: _UP4_TGAACTTAATCGAAAAGGAT
  • BKK39410 (nupC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGTGTTTCTCCTTTAT, downstream forward: _UP4_TGAACTTAATCGAAAAGGAT

    • References

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