hmoB [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

heme monooxygenase

locus: BSU10100

pI: 5.22

mw: 18.00 kDa

function: degradation of heme, acquisition of iron

product: heme monooxygenase

essential: no

synonyms: yixC, yhgC

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.3|Acquisition of iron / Other]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.1|Acquisition of iron / Other]

[SW|Categories] containing this gene/protein

• [SW|acquisition of iron]

Gene

Coordinates on the chromosome (coding sequence): 1,083,229 -> 1,083,729

The protein

Catalyzed reaction/ biological activity

• binds hemin ''in vitro'' with ~1:1 stoichiometry and degrade hemin in the presence of an electron donor [Pubmed|21873409]

Structure

• [PDB|3TVZ] [Pubmed|22531134]

Expression and Regulation

Operon

• ''[protein|search|hmoB]'' [Pubmed|8335642]

Regulation

• constitutively expressed [Pubmed|21873409]

References

• 8335642,22531134,24582752,21873409