SubtiBank SubtiBank
rsiW [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

rsiW [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

anti-SigW
locus
BSU01740
pI
6.65
mw
23.00 kDa
function
control of SigW activity
product
anti-SigW
essential
no
synonyms
ybbM
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|sigma factors and their control], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|SigW regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    195,426 -> 196,052

    The protein

    Protein family

  • anti-sigma-W factor family (according to Swiss-Prot)

    • Effectors of protein activity

  • degraded by [protein|search|RasP] and [protein|search|PrsW] under conditions of alkali shock or in the presence of antimicrobial peptides, respectively. This results in the release of [protein|search|SigW]

    • [SW|Localization]

  • membrane (according to Swiss-Prot)

    • [SW|Interactions]

  • [protein|search|PrsW]-[protein|search|RsiW] (proteolysis) [Pubmed|17020587]
  • [protein|search|RasP]-[protein|search|RsiW] (proteolysis)
  • [protein|search|RsiW]-[protein|search|SigW] [Pubmed|14993308]

    • Expression and Regulation

    Operon

  • ''[protein|search|sigW]-[protein|search|rsiW]'' [Pubmed|12207695]

    • [SW|Sigma factor]

  • [protein|search|SigW] [Pubmed|12207695]

    • Regulation

  • induced under conditions of alkali shock or in the presence of the toxin [protein|search|SdpC] ([protein|search|SigW]) [Pubmed|12207695]
  • repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|12076816]

    • Regulatory mechanism

  • [protein|search|AbrB]: transcription repression [Pubmed|12076816]

    • Additional information

  • the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]

    • Labs working on this gene/protein

  • [SW|Thomas Wiegert], University of Bayreuth, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/Thomas%20Wiegert-Dateien/Thomas%20Wiegert.html Homepage]

    • References

    Reviews==

  • Additional reviews:''' [Pubmed|22381678]
  • 20836086

    • Original Publications

  • 17020587,14993308,16816000,18599827,12207695,16899079,15130127,12884008,12076816,19889088,14993308