ysdB

control of [protein|search|SigW ]activity, survival of heat stress

locus: BSU_28830

pI: 9.41

mw: 15.43 kDa

protein length: 130 aa

gene length: 393 bp

function: survival of heat stress

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 2,951,490 2,951,882

Phenotypes of a mutant

• constitutive [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW] activity [Pubmed|10960106]

The protein

[SW|Domains]

• contains a transmembrane domain

[SW|Localization]

• integral membrane protein [Pubmed|16816000]

Expression and Regulation

Operons

• genes: [gene|4E3ED9AB8EB465B9D4DDF58F69D277F35CC2A78C|ysdB]
  description: [Pubmed|9987136]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|9987136], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]

  regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528], [protein|search|SigW] [Pubmed|9987136]

Biological materials

Mutant

• MGNA-A984 (ysdB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/984 NBRP B. subtilis, Japan]
• BKE28830 ([gene|4E3ED9AB8EB465B9D4DDF58F69D277F35CC2A78C|ysdB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTGTGAAGGCACCTCC, downstream forward: _UP4_GAGCGTTAAACGCTTTTCTG
• BKK28830 ([gene|4E3ED9AB8EB465B9D4DDF58F69D277F35CC2A78C|ysdB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTGTGAAGGCACCTCC, downstream forward: _UP4_GAGCGTTAAACGCTTTTCTG

References

Reviews

• Additional reviews:''' [Pubmed|22381678]

Original Publications

• 10960106,9987136,15805528,16816000