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gamP [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]
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gamP [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

glucosamine-specific phosphotransferase system, EIICBA of the PTS
Locus
BSU02350
Isoelectric point
5.47
Molecular weight
67.00 kDa
Function
glucosamine uptake and phosphorylation
Product
glucosamine-specific phosphotransferase system, EIICBA
Essential
no
E.C.
2.7.1.69
Synonyms
ybfS, yzfA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Cell wall degradation/ turnover → Utilization of cell wall components
  • Cellular processes → Transporters → Phosphotransferase system → Sugar specific PTS proteins
  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of amino sugars
  • Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of amino sugars
  • Groups of genes → Membrane proteins
  • Groups of genes → Phosphoproteins → Phosphorylation on a Cys residue
  • Groups of genes → Phosphoproteins → Phosphorylation on a His residue

    • Categories containing this gene/protein

  • cell wall degradation/ turnover, phosphotransferase systems, utilization of specific carbon sources, membrane proteins, phosphoproteins

    • This gene is a member of the following regulons

  • GamR regulon

    • Gene

    Coordinates on the chromosome (coding sequence)
    254,907 -> 256,802

    Phenotypes of a mutant

  • delayed growth with glucosamine as the single carbon source PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)

    • Protein family

  • PTS permease, glucose permease (Glc) family PubMed

    • Paralogous protein(s)

  • NagP

    • Localization

  • membrane PubMed

    • Interactions

  • GamP-[PtsH|search|HPr]

    • Expression and Regulation

    Operon

  • gamA-gamP PubMed

    • Sigma factor

  • SigA PubMed

    • Regulation

  • induced by glucosamine (GamR) PubMed

    • Regulatory mechanism

  • GamR: transcription repression PubMed

    • Biological materials

    Mutant

  • QB6098 (aphA3), available in Stülke lab

    • References

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