SubtiBank SubtiBank
helD
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

helD

DNA 3-5 helicase IV, stimulates transcription in an ATP-dependent manner by enhancing transcriptional cycling and elongation
Locus
BSU_33450
Isoelectric point
6.08
Molecular weight
89.74 kDa
Protein length
774 aa Sequence Blast
Gene length
2325 bp Sequence Blast
Function
transcription, DNA repair/ recombination
Product
DNA 3-5 helicase IV
Essential
no
E.C.
3.6.4.12
Synonyms
yvgS
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Information processing → Genetics → DNA repair/ recombination
  • Information processing → Genetics → DNA repair/ recombination → Other proteins

    • Gene

    Coordinates
    3,434,327 3,436,651

    The protein

    Catalyzed reaction/ biological activity

  • ATP + H2O --> ADP + H+ + phosphate (according to UniProt)

    • Protein family

  • helicase family (according to UniProt)

    • Domains

  • UvrD-like helicase ATP-binding domain (aa 212-610) (according to UniProt)

    • Structure

  • 3DMN (C-terminal domain of the protein from Lactobacillus plantarum, 39% identity)

    • Localization

  • cytoplasm (according to UniProt)

    • Additional information

  • HelD may interact with RNA polymerase PubMed

    • Expression and Regulation

    Operons

    Genes
    helD
    Description
    PubMed
    view in new tab

    Biological materials

    Mutant

  • MGNA-A456 (yvgS::erm), available at the NBRP B. subtilis, Japan
  • 1A899 ( helD::erm), available at BGSC
  • BKE33450 (helD::erm trpC2) available at BGSC as well as in Fabian Commichau's and Jörg Stülke's labs, PubMed, upstream reverse: _UP1_CATGAACGGCACCTCCAGAA, downstream forward: _UP4_TGAAGAGAAGGGAGTCCTTC
  • BKK33450 (helD::kan trpC2) available at BGSC and in Jörg Stülke's lab, PubMed, upstream reverse: _UP1_CATGAACGGCACCTCCAGAA, downstream forward: _UP4_TGAAGAGAAGGGAGTCCTTC

    • References

    Loading