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med

lipoprotein, positive regulator of comK, stimulates KinD-dependent phosphorylation of Spo0A
Locus
BSU_11300
Isoelectric point
4.60
Molecular weight
35.16 kDa
Protein length
317 aa Sequence Blast
Gene length
954 bp Sequence Blast
Function
regulation of competence
Product
positive regulator of comK
Essential
no
Synonyms
yjaW
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Genetics → Genetic competence
  • Lifestyles → Exponential and early post-exponential lifestyles → Genetic competence

    • Gene

    Coordinates
    1,206,629 1,207,582

    Phenotypes of a mutant

  • impaired biofilm formation PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • stimulates KinD-dependent phosphorylation of Spo0A PubMed

    • Protein family

  • BMP lipoprotein family (with NupN, according to UniProt)

    • Structure

  • 2HQB (from B. halodurans, 49% identity) PubMed

    • Localization

  • cell surface PubMed

    • Expression and Regulation

    Operons

    Genes
    yjaV-med-comZ
    Description
    PubMed

    Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon
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    Genes
    med-comZ
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • Spo0A: repression, PubMed, in Spo0A regulon

    • Regulation

  • repressed under conditions that trigger sporulation (Spo0A) PubMed
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    Genes
    yjaU-yjaV-med-comZ
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE11300 (med::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTCATGTTCAACTCCTT, downstream forward: _UP4_AACGAGTAATGGAGTGACGT
  • BKK11300 (med::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTCATGTTCAACTCCTT, downstream forward: _UP4_AACGAGTAATGGAGTGACGT

    • References

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