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med

lipoprotein, positive regulator of comK, stimulates KinD-dependent phosphorylation of Spo0A
Locus
BSU_11300
Isoelectric point
4.60
Molecular weight
35.16 kDa
Protein length
317 aa Sequence Blast
Gene length
954 bp Sequence Blast
Function
regulation of competence
Product
positive regulator of comK
Essential
no
Synonyms
yjaW

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,206,629 1,207,582

Phenotypes of a mutant

  • impaired biofilm formation PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • stimulates KinD-dependent phosphorylation of Spo0A PubMed
  • Protein family

  • BMP lipoprotein family (with NupN, according to UniProt)
  • Structure

  • 2HQB (from B. halodurans, 49% identity) PubMed
  • Localization

  • cell surface PubMed
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon
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    Genes
    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • Spo0A: repression, PubMed, in Spo0A regulon
  • Regulation

  • repressed under conditions that trigger sporulation (Spo0A) PubMed
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    Biological materials

    Mutant

  • BKE11300 (med::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTCATGTTCAACTCCTT, downstream forward: _UP4_AACGAGTAATGGAGTGACGT
  • BKK11300 (med::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTCATGTTCAACTCCTT, downstream forward: _UP4_AACGAGTAATGGAGTGACGT
  • References

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