dgcP [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

diguanylate cyclase

locus: BSU29650

pI: 5.00

mw: 65.00 kDa

function: synthesis of c-di-GMP

product: diguanylate cyclase

essential: no

synonyms: ytrP

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.3|Metabolism of signalling nucleotides]

[SW|Categories] containing this gene/protein

• [SW|metabolism of signalling nucleotides]

Gene

Coordinates on the chromosome (coding sequence): 3,033,696 -> 3,035,435

The protein

Catalyzed reaction/ biological activity

• synthesis of c-di-GMP from two molecules of GTP [Pubmed|23893111]

[SW|Domains]

• contains an N-terminal GAF domain [Pubmed|23893111]
• contains a C-terminal [SW|GGDEF domain] [Pubmed|22821967]

Expression and Regulation

Operon

• ''[protein|search|dgcP]'' (according to [http://dbtbs.hgc.jp/COG/prom/ytrP.html DBTBS])

Biological materials

Mutant

• GP1591 (tet) available in [SW|Jörg Stülke]'s lab

References

• 23893111,22821967