SubtiBank SubtiBank
yoaA
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yoaA

similar to spermidine/spermine N-acetyltransferase
locus
BSU_18530
pI
5.92
mw
18.89 kDa
protein length
177 aa Sequence Blast
gene length
534 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    2,020,611 2,021,144

    The protein

    Protein family

  • [SW|Acetyltransferase family] (according to UniProt)

    • Paralogous protein(s)

  • [protein|F92B7EC7A00BF295666D68613932D239F92C7347|YkkB], [protein|18FA5EFCD78C74296F9E52A64DA4A9D635944528|YnaD]

    • [SW|Domains]

  • [SW|N-acetyltransferase domain] (aa 10-177) (according to UniProt)

    • Structure

  • [PDB|5WIF] (from Yersinia pestis, 29% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|928CD0278328BB8642F7D560E42C13D74B4F1341|yoxC]-[gene|8C5ECDA04FA75F6FFA8625431AAC6855D8A1DB08|yoxB]-[gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]
    description
    [Pubmed|10482513]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|10482513,15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|10482513,15805528]
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    Biological materials

    Mutant

  • MGNA-A832 (yoaA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/832 NBRP B. subtilis, Japan]
  • GP1248 (''yoaA''::''tet''), available in [SW|Jörg Stülke]'s lab
  • GP1255 (''[gene|17C3F56CE859BCD7A282C144C46CC92D3506ABF6|acuA]''::''kan'' ''[gene|6072A6EF0766F3D1B1616A20CDC36CCDC6CBDA71|yjcK]''::''cat'' ''[gene|18FA5EFCD78C74296F9E52A64DA4A9D635944528|ynaD]''::''spec'' ''[gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]''::''tet''), available in [SW|Jörg Stülke]'s lab
  • BKE18530 ([gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCAACCACTCCCCACGT, downstream forward: _UP4_TGACGGTATTCTCTTGGTCT
  • BKK18530 ([gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCAACCACTCCCCACGT, downstream forward: _UP4_TGACGGTATTCTCTTGGTCT

    • References

  • 10482513,15805528