gatC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

production of glutamyl-tRNA(Gln)

locus: BSU06670

pI: 4.00

mw: 10.00 kDa

function: translation

product: glutamyl-tRNA(Gln) amidotransferase (subunit C)

essential: yes

ec: 6.3.5.7

synonyms: yerL, yedA

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.10|Aminoacyl-tRNA synthetases]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|essential genes], [SW|phosphoproteins]

Gene

Coordinates on the chromosome (coding sequence): 728,732 -> 729,022

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• ATP L-glutamyl-tRNA(Gln) L-glutamine = ADP phosphate L-glutaminyl-tRNA(Gln) L-glutamate (according to Swiss-Prot)

Protein family

• gatC family (according to Swiss-Prot)

Modification

• phosphorylated on Arg-3 [Pubmed|22517742]

Structure

• [PDB|2DF4] ([protein|search|GatA]-[protein|search|GatB]-[protein|search|GatC] complex from ''Staphylococcus aureus'') [Pubmed|16809541]

[SW|Interactions]

• [protein|search|GatA]-[protein|search|GatB]-[protein|search|GatC]
• ([protein|search|GatA]-[protein|search|GatB]-[protein|search|GatC])-[protein|search|GltX]-[protein|search|trnS-Gln] (the [SW|transamidosome]) [Pubmed|20882017], see a [http://www.nature.com/nature/journal/v467/n7315/fig_tab/nature09411_F3.html model of the interaction] [Pubmed|20882017]

References

• 9342321,20882017,22517742,16809541