recS [2019-06-06 11:59:59]

ATP-dependent DNA helicase

locus: BSU23020

pI: 6.23

mw: 56.34 kDa

protein length: 496 aa

gene length: 1491 bp

function: replication reactivation pathway

product: ATP-dependent DNA helicase

essential: no

synonyms: recS,ypbC

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

Gene

Coordinates: 2,406,922 2,408,412

The protein

Protein family

• [SW|helicase family] (according to UniProt)
• RecQ subfamily (according to Swiss-Prot)

Paralogous protein(s)

• [protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|RecQ]

Structure

• [PDB|4Q47] ([protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|RecQ] from Deinococcus radiodurans, corresponds to aa 8 ... 394, 38% identity) [pubmed|25243132]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Biological materials

Mutant

• 1A893 (no resistance), [Pubmed|16020779], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A893&Search=1A893 BGSC]
• BKE23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT
• BKK23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT

References

Reviews

• 12427530,21047263,22933559

Original publications

• 17853894,25246477,25243132