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recS
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recS

ATP-dependent DNA helicase
locus
BSU_23020
pI
6.23
mw
56.34 kDa
protein length
496 aa Sequence Blast
gene length
1491 bp Sequence Blast
function
replication reactivation pathway
product
ATP-dependent DNA helicase
essential
no
synonyms
recS,ypbC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

    • Gene

    Coordinates
    2,406,922 2,408,412

    The protein

    Catalyzed reaction/ biological activity

  • ATP + H2O --> ADP + H+ + phosphate (according to UniProt)

    • Protein family

  • [SW|helicase family] (according to UniProt)

    • Paralogous protein(s)

  • [protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|RecQ]

    • [SW|Domains]

  • [SW|Helicase ATP-binding domain] (aa 25-192) (according to UniProt)
  • [SW|Helicase C-terminal domain] (aa 219-363) (according to UniProt)

    • Structure

  • [PDB|4Q47] ([protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|RecQ] from Deinococcus radiodurans, corresponds to aa 8 ... 394, 38% identity) [pubmed|25243132]

    • [SW|Localization]

  • cytoplasm (according to UniProt)

    • Biological materials

    Mutant

  • GP3531 (Δ[gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::kan), available in [SW|Jörg Stülke]'s lab
  • 1A893 (no resistance), [Pubmed|16020779], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A893&Search=1A893 BGSC]
  • BKE23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT
  • BKK23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT

    • References

    Reviews

  • 12427530,21047263,22933559

    • Original publications

  • 17853894,25246477,25243132