outer spore coat protein, spore associated transglutaminase
function
introduction of crosslinks in the spore coat protein GerQ
product
spore associated transglutaminase
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.5|Class V][SW|Categories] containing this gene/protein
[SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|GerE regulon], [SW|SigE regulon], [SW|SigK regulon]Gene
Coordinates on the chromosome (coding sequence)
3,212,591 -> 3,213,328
The protein
Catalyzed reaction/ biological activity
Protein glutamine alkylamine = protein N(5)-alkylglutamine NH3 (according to Swiss-Prot), temperature-dependent modification of the coat proteins such as [protein|search|GerQ] (together with [protein|search|YabG]) [Pubmed|16751597]Protein family
bacillus TGase family (according to Swiss-Prot)Structure
[PDB|4P8I] [Pubmed|26322858][PDB|4PA5] (complexed with cystamine) [Pubmed|26322858][SW|Localization]
outer spore coat, localization depends on [protein|search|CotE] [Pubmed|22171814]Expression and Regulation
Operon
''[protein|search|tgl]'' [Pubmed|9274030][SW|Sigma factor]
[protein|search|SigK] [Pubmed|15699190,12501297], [protein|search|SigE] [Pubmed|15383836]Regulation
expressed late during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE]) [Pubmed|15383836,15699190,12501297]Regulatory mechanism
[protein|search|GerE]: transcription repression [Pubmed|15383836]Biological materials
Mutant
1S122 ( ''tgl''::''erm''), [Pubmed|15317760], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S122&Search=1S122 BGSC]Labs working on this gene/protein
[SW|Adriano Henriques], Lisbon, Portugal [http://www.itqb.unl.pt/research/biology/microbial-development homepage]References
Reviews
Original Publications
18249137,22171814,12501297,16267299,11193401,16751597,9274030,15699190,15383836,26322858 
