yesM [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

two-component sensor kinase

locus: BSU06950

pI: 7.28

mw: 66.00 kDa

function: unknown

product: two-component sensor kinase

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

[SW|Categories] containing this gene/protein

• [SW|protein modification], [SW|transcription factors and their control], [SW|membrane proteins], [SW|phosphoproteins]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon]

Gene

Coordinates on the chromosome (coding sequence): 758,719 -> 760,452

The protein

Catalyzed reaction/ biological activity

• autophosphorylation, phosphorylation of [protein|search|YesN]

[SW|Domains]

• two transmembrane segments, C-terminal histidine phosphotransferase domain

Modification

• autophosphorylation on a His residue

[SW|Localization]

• cell membrane (according to Swiss-Prot)

[SW|Interactions]

• [protein|search|YesM]-[protein|search|YesN]

Expression and Regulation

Regulation

• repressed by glucose (7.7-fold) ([protein|search|CcpA]) [Pubmed|12850135]

Regulatory mechanism

• [protein|search|CcpA]: transcription repression

References

• 10094672,12850135