lrpA

transcriptional regulator (Lrp family) involved in repression of [gene|BAE8062DA8538C9C83FFBA9684BECE9613EEFD2F|glyA] transcription and [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|KinB]-dependent [SW|sporulation]

locus: BSU_05050

pI: 7.78

mw: 15.30 kDa

protein length: 136 aa

gene length: 411 bp

function: repression of [gene|BAE8062DA8538C9C83FFBA9684BECE9613EEFD2F|glyA] transcription and [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|KinB]-dependent [SW|sporulation]

product: transcription regulator (Lrp family)

essential: no

synonyms: yddO

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay]

Gene

Coordinates: 551,519 551,929

The protein

Protein family

• ([SW|Lrp family])

[SW|Domains]

• [SW|HTH asnC-type domain] (aa 2-63) (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|49F609C55238C24045CE4A946C417406C8CAAF9D|lrpA]
  description: [pubmed|22383849]

Biological materials

Mutant

• MGNA-C107 (yddO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2105 NBRP B. subtilis, Japan]
• BKE05050 ([gene|49F609C55238C24045CE4A946C417406C8CAAF9D|lrpA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTTGTATCCTTTCT, downstream forward: _UP4_TAGTTAACTTTATAAAACGG
• BKK05050 ([gene|49F609C55238C24045CE4A946C417406C8CAAF9D|lrpA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTTGTATCCTTTCT, downstream forward: _UP4_TAGTTAACTTTATAAAACGG