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ykgB [2017-8-11 16:0:3]
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ykgB [2017-8-11 16:0:3]

6-phosphogluconolactonase, general stress protein
Locus
BSU13010
Isoelectric point
5.15
Molecular weight
38.26 kDa
Protein length
349 aa Sequence Blast
Gene length
1047 bp Sequence Blast
Function
pentose phosphate pathway
Product
6-phosphogluconolactonase
Essential
no
E.C.
3.1.1.31
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Carbon core metabolism → Pentose phosphate pathway
  • Lifestyles → Coping with stress → General stress proteins (controlled by SigB)

    • Gene

    Coordinates
    1,369,876 → 1,370,925

    The protein

    Catalyzed reaction/ biological activity

  • 6-phosphogluconolactone -→ 6-phosphogluconate (pentose phosphate pathway) PubMed

    • Protein family

  • cycloisomerase 2 family (according to Swiss-Prot)

    • Structure

  • 3HFQ (from Lactobacillus plantarum, 42% identity)

    • Expression and Regulation

    Operons

    Genes
    ykgA-ykgB
    Description
    PubMed

    Sigma factors

  • SigB: sigma factor, PubMed, in SigB regulon

    • Regulation

  • induced by stress (SigB) PubMed
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    Biological materials

    Mutant

  • MGNA-A754 (ykgB::erm), available at the NBRP B. subtilis, Japan

    • FLAG-tag construct

  • GP1402 (spc, based on pGP1331), available in the Stülke lab

    • Antibody

  • **

    • References

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