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ythP
similar to [SW|ABC transporter] (ATP-binding protein)
product
[SW|ABC transporter] (ATP-binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.6|Exporters of unknown function][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
3,071,400 3,072,110
The protein
Protein family
[SW|ABC transporter superfamily] (according to UniProt)Paralogous protein(s)
[protein|59A7B26F810D7FEB07C176A8B2ECF6B83803DE49|EcsA] [SW|Domains]
[SW|ABC transporter domain] (aa 4-255) (according to UniProt)Structure
[PDB|4RVC] (from Geobacillus kaustophilus, 44% identity) [pubmed|25724946]Expression and Regulation
Operons
genes
[gene|47C1A154AF6F67CA507A9F4FEA9576E7131EFB6D|ythP]-[gene|3ACDFBD5615510FA015486C7A3C7023226EC3476|ythQ]
description
[Pubmed|11866510]
sigma factors
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|11866510,12207695], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]regulation
expressed under conditions of cell wall stress ([protein|search|SigW]) [Pubmed|11866510,12207695]view in new tabBiological materials
Mutant
MGNA-A817 (ythP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/817 NBRP B. subtilis, Japan]BKE30010 ([gene|47C1A154AF6F67CA507A9F4FEA9576E7131EFB6D|ythP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE30010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACTCACTCACCTCCAA, downstream forward: _UP4_AAGGCAGTTCAAGGTGATCGBKK30010 ([gene|47C1A154AF6F67CA507A9F4FEA9576E7131EFB6D|ythP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK30010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACTCACTCACCTCCAA, downstream forward: _UP4_AAGGCAGTTCAAGGTGATCGReferences
10092453,11866510,12207695,25724946