SubtiBank SubtiBank
cotW [Tue Oct 25 2016 17:07:35 GMT+0200 (CEST)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

cotW [Tue Oct 25 2016 17:07:35 GMT+0200 (CEST)]

outer spore coat protein (insoluble fraction), formation of the spore crust
locus
BSU11770
pI
9.00
mw
12.00 kDa
function
resistance of the spore
product
spore coat protein (insoluble fraction)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.5|Class V]
  • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|GerE regulon], [SW|SigE regulon], [SW|SigK regulon], [SW|SpoIIID regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,251,273 -> 1,251,590

    The protein

    [SW|Localization]

  • spore crust, localization depends on [protein|search|CotX], [protein|search|CotY], and [protein|search|CotZ] [Pubmed|23202530]
  • [SW|Interactions]

  • [protein|search|CotV]-[protein|search|CotW] [Pubmed|19304857]
  • Expression and Regulation

    Operon

  • ''[protein|search|cotV]-[protein|search|cotW]-[protein|search|cotX]'' [Pubmed|7519271]
  • [SW|Sigma factor]

  • [protein|search|SigE] [Pubmed|15383836] , [protein|search|SigK] [Pubmed|15699190,7519271]
  • Regulation

  • expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE], [SW|SpoIIID]) [Pubmed|15383836]
  • repressed by casamino acids [Pubmed|12107147]
  • expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
  • Regulatory mechanism

  • [protein|search|GerE]: transcription activation [Pubmed|15383836]
  • [SW|SpoIIID]: transcription activation [Pubmed|15383836]
  • References

    Reviews

  • 23202530
  • Original publications

  • 7519271,19304857,21665972,12107147,15383836,22171814,25872412