qdoR [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

transcriptional regulator (TetR family), control of qdoI-yxaH and lmrA-lmrB

Locus: BSU39990

Isoelectric point: 6.11

Molecular weight: 20.00 kDa

Function: control of quercetin utilization

Product: transcriptional regulator

Essential: no

Synonyms: yxaF

Genomic Context

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Categories containing this gene/protein

• Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other
• Lifestyles → Coping with stress → Resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

Categories containing this gene/protein

• transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

• LmrA regulon, QdoR regulon

Gene

Coordinates on the chromosome (coding sequence): 4,107,352 -> 4,107,927

The protein

Protein family

• TetR family

Paralogous protein(s)

• LmrA

Effectors of protein activity

• flavonoids such as quercetin act as molecular inducers and result in release from DNA targets PubMed

Structure

• 1SGM

Expression and Regulation

Operon

• qdoR PubMed

Regulation

• induced by flavonoids such as quercetin (QdoR, LmrA) PubMed

Regulatory mechanism

• LmrA: transcription repression PubMed
• QdoR: transcription repression PubMed

Labs working on this gene/protein

• Yasutaro Fujita, University of Fukuyama, Japan

References

Reviews

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Original publications

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