yvqK [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

ATP:cob(I)alamin adenosyltransferase

locus: BSU33150

pI: 5.00

mw: 21.00 kDa

function: unknown

product: ATP:cob(I)alamin adenosyltransferase

essential: no

ec: 2.5.1.17

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.13|Biosynthesis/ acquisition of cobalamine (B12))]
• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

[SW|Categories] containing this gene/protein

• [SW|poorly characterized/ putative enzymes]

This gene is a member of the following [SW|regulons]

• [SW|B12 riboswitch]

Gene

Coordinates on the chromosome (coding sequence): 3,400,537 -> 3,401,118

The protein

Catalyzed reaction/ biological activity

• ATP cob(I)yrinic acid a,c-diamide = triphosphate adenosylcob(III)yrinic acid a,c-diamide (according to Swiss-Prot)

Protein family

• Cob(I)alamin adenosyltransferase family (according to Swiss-Prot)

Structure

• [PDB|1RTY]

Expression and Regulation

Operon

• ''[SW|yvrC]-[SW|yvrB]-[SW|yvrA]-[SW|yvqK]'' [Pubmed|]

Regulation

• expression is decreased in the presence of cobalamin (vitamin B12) ([SW|B12 riboswitch]) [Pubmed|14704351]

Regulatory mechanism

• [SW|B12 riboswitch]: transcription termination upon binding of B12 [Pubmed|14704351]

References

• 17588214,14704351